Project Description
Instrument Controlled Microfluidic Cartridge for Sample Concentration
Our Client had designed an instrument to concentrate biological samples, and asked us to design a disposable cartridge to work with their existing design.
The Cartridge Design
- Highly efficient rapid filtration-based, fractionation concentration platform that concentrates biological particles that are suspended in liquid-form from a feed suspension
- Instrument-actuated 7 state microfluidic valve in a sliding configuration. Low-cost, reliable and high-pressure capable
- Achieved precision engagement between the instrument and cartridge
- Multiple pressure and vacuum interfaces to the instrument
- Ultrasonically welded assembly for microfluidic channel sealing
- Hermetically sealed internal filter media
- Geared mechanism deploys a 100 mm tube for collection of sample from the bottom of the sample container
- Developed unique method to reduce velocity of cartridge output while maintaining pressure requirements
US Patent Application: https://www.google.com/patents/US20150152467
Expertise Employed
While all projects benefit from our development process and expertise in design, engineering, and in-house rapid prototyping, this project highlights our expertise in: