Our Client had designed an instrument to concentrate biological samples, and asked us to design a disposable cartridge to work with their existing design.

The Cartridge Design

• Highly efficient rapid filtration-based, fractionation concentration platform that concentrates biological particles that are suspended in liquid-form from a feed suspension
• Instrument-actuated 7 state microfluidic valve in a sliding configuration. Low-cost, reliable and high-pressure capable
• Achieved precision engagement between the instrument and cartridge
• Multiple pressure and vacuum interfaces to the instrument
• Ultrasonically welded assembly for microfluidic channel sealing
• Hermetically sealed internal filter media
• Geared mechanism deploys a 100 mm tube for collection of sample from the bottom of the sample container
• Developed unique method to reduce velocity of cartridge output while maintaining pressure requirements

US Patent Application:  https://www.google.com/patents/US20150152467

Expertise Employed
While all projects benefit from our development process and expertise in design, engineering, and in-house rapid prototyping, this project highlights our expertise in:

• Mechanical Design and Engineering
• Materials Selection
• Microfluidics and Fluid Dynamics